Body Pharm BPC-157 + TB-500

The BPC-157 + TB-500 research pen is a pre-filled multi-dose injectable pen that carries the two regenerative peptides co-dissolved 50/50 in a single 3 ml cartridge, and it is sold in Spain solely for in vitro and laboratory research purposes at €129. That is 16 mg of BPC-157 and 16 mg of TB-500: 32 mg of peptide in total. Both BPC-157 and TB-500 appear on the prohibited list of WADA (the World Anti-Doping Agency): TB-500 among the thymosin β4 derivatives of section S2 (peptide hormones and growth factors) and BPC-157 among the non-approved substances of section S0 [6]. This page explains how the dose is set on the dial, describes the procedures for batch traceability and sets out in detail the regulatory status for 2026 before you go through to checkout.

BPC-157 + TB-500 pen: what you need to know

• One pen, one cartridge, one dial: 16 mg of BPC-157 and 16 mg of TB-500 co-dissolved 50/50, 32 mg of peptide in total
• The number you set on the dial is the dose of each peptide: 0.25 mg dialled delivers 0.25 mg of BPC-157 and 0.25 mg of TB-500, which is to say 0.5 mg of peptide in total
• The 1:1 ratio is fixed inside the cartridge, so it cannot drift between one administration and the next
• Neither one of the two peptides is authorised as a medicine for use in people; the pen is sold solely for the purposes of research
• Batch traceability is built in: every pen carries a unique batch number that is linked to the HPLC purity data, to the mass-spectrometry confirmation of identity and to a certificate of analysis

What is the BPC-157 + TB-500 blend?

A BPC-157 + TB-500 blend is the combination of two synthetic regenerative peptides in a single cartridge: BPC-157, a 15-amino-acid pentadecapeptide derived from a protective sequence found in human gastric juice, and TB-500, a synthetic fragment of the 43-amino-acid protein thymosin beta-4. In this pen the two are co-dissolved 50/50 in the same cartridge, 16 mg of each, and they are administered together in a single injection. Research staff in Spain buy it in order to study complementary pathways of tissue repair with a ratio between the two peptides that is held fixed.

BPC-157: the stomach-derived pentadecapeptide

BPC-157 (Body Protection Compound-157) is a stable synthetic pentadecapeptide of 15 amino acids originally isolated from a larger protective protein in gastric juice. Preclinical work, for the most part by Sikiric and colleagues, has studied its activity in models of gastrointestinal ulcers, in models of tendon and ligament repair and in endothelial/VEGF-dependent (vascular endothelial growth factor) angiogenesis pathways. To date, no large-scale study in humans has clarified its mechanism in vivo, a translational gap that has been pointed out in recent commentaries [2].

TB-500: the thymosin beta-4 analogue

TB-500 is a synthetic analogue or fragment of thymosin beta-4, a 43-amino-acid actin-sequestering protein involved in cell migration, angiogenesis and wound healing [1]. The exact sequence and molecular mass of the TB-500 fragment vary from one supplier to another and are not published separately for each product; the wider research-chemicals market usually refers to a fragment derived from thymosin beta-4 in the 4.9–5.1 kDa range.

Why they are combined

The two peptides are directed at pathways that are mechanistically distinct. BPC-157 is studied most intensively in gastric and connective-tissue models; the work on TB-500 focuses on the systemic regulation of actin and on angiogenesis. For experimental designs that need to cover both axes in parallel, read our complete BPC-157 + TB-500 dosing protocol and the guide BPC-157 vs. TB-500: how the two peptides compare.

One cartridge, one dial: how the dose is set

This is a single pen, with a single 3 ml cartridge and a single dial. Inside it go the two peptides, co-dissolved 50/50: 16 mg of BPC-157 and 16 mg of TB-500, which makes 32 mg of peptide in total.

The number on the dial is the dose of each peptide

The dial sets the dose directly in milligrams, and that number is the dose of each peptide, not the sum of the two. If you dial 0.25 mg, you deliver 0.25 mg of BPC-157 and 0.25 mg of TB-500, which is to say 0.5 mg of peptide in total. If you dial 0.5 mg, you deliver 0.5 mg of each, 1 mg in total. There is nothing to split and no need to keep two separate tallies: a single figure describes the complete administration.

The ratio is fixed inside the cartridge

Both peptides are dissolved together on the filling line before the pen is sealed, so the 1:1 ratio is fixed once, under controlled conditions. That ratio is the same in the first dose from the cartridge and in the last, which allows a research team to compare the data from week three with the data from week one without having to re-validate anything. It is the single most important factor for reproducibility from one session to the next when two peptides are being administered together.

The guidance on dose and frequency is in our complete BPC-157 + TB-500 dosing protocol; the mechanistic rationale for the combination is provided by the guide BPC-157 vs. TB-500: how the two peptides compare.

Body Pharm BPC-157 + TB-500 pen: product specification

The Body Pharm BPC-157 + TB-500 pen is a pre-mixed, sealed injectable research device that contains both peptides co-dissolved 50/50 in a single cartridge, is delivered with a batch-specific certificate of analysis and is shipped under refrigerated conditions solely for research purposes. The dose is set on the dial, in milligrams.

Specification table

What the certificate of analysis covers

Every batch is delivered with a CoA that documents the purity by HPLC (high-performance liquid chromatography) of both of the peptides, the mass-spectrometry confirmation of the identity of the sequence, the appearance and a screen for residual solvents. An endotoxin assay is carried out whenever the batch is intended for sterile-fill workflows. The CoAs are issued in accordance with internal quality procedures aligned with the principles of Annex 1 of EU GMP (good manufacturing practice) for the handling of sterile products.

For the examples of dose and frequency, read the complete BPC-157 + TB-500 dosing protocol; the mechanistic background, with the sequence and pathway details, is provided by the guide BPC-157 vs. TB-500: how the two peptides compare.

Quality, purity and batch traceability

Every pen we ship is traceable from the filling line to the shipping label by means of a unique batch number, printed on the device and repeated on its certificate of analysis. In our batch-handling process, each filling run is sealed under controlled conditions at the laboratory of origin in the EU, is dose-validated on a sample of units and is not released until the CoA has been signed off against internal specifications aligned with the principles of Annex 1 of EU GMP for the handling of sterile products. Research staff can request the full batch file (CoA, name of the laboratory of origin, filling date) from our support service by quoting the batch number.

What HPLC purity actually tells you

High-performance liquid chromatography separates the peptide from the by-products of synthesis, from truncated sequences and from residual solvents, and then quantifies each of the fractions. A purity value of, for example, ≥ 98% means that at least 98% of the mass detected corresponds to the intended peptide; the remaining ≤ 2% consists of impurities that have been characterised. In BPC-157 + TB-500 blends, both peptides are analysed separately, so that a single "blend purity" figure cannot conceal a weak component. Other suppliers typically advertise an HPLC purity of ≥ 99% on comparable blends [4]; the HPLC purity threshold for each batch is stated on its certificate of analysis.

Accessing the documentation for your batch

Quote the batch code at checkout, or send it to us by email after delivery, and we will send the CoA back to you as a PDF, complete with the HPLC chromatograms and the mass-spectrometry confirmation of identity, within the space of one working day. For protocol decisions, once the CoA is available, the complete BPC-157 + TB-500 dosing protocol guides the allocation of dose and frequency.

Regulatory context: for research use only

BPC-157 and TB-500 are not authorised medicines and are not authorised for use in people; here they are sold solely as research chemicals for in vitro and analytical work. Regardless of the "research use only" labelling, Body Pharm does not supply preparations for administration to people [5].

That is what sets the pen apart from any authorised medicine dispensed in a pharmacy: there is no marketing authorisation, no summary of product characteristics and no patient leaflet. Both peptides also appear on the WADA prohibited list (TB-500 in section S2, growth factors; BPC-157 in section S0, non-approved substances), which is relevant in the context of sport but is independent of their classification as a medicine [6]. Buyers who are responsible for institutional compliance should review their research-governance framework before placing an order.

Body Pharm supplies verified research buyers only. If you are still comparing the two peptides before you decide, the BPC-157 vs. TB-500 comparison guide is available right alongside this product page.

Notice: This product is sold solely for laboratory research and as an analytical reference. Not for human or animal consumption, not for diagnostic purposes and not for in vivo administration. No therapeutic claims are made or implied.

Shipping, packaging and returns

Orders within Spain are sent with tracking for a flat shipping fee and generally arrive within a period of 3–5 working days. Every parcel is sent in plain, unbranded outer packaging, and you receive a tracking number by email at the moment of dispatch, so that the purchasing department is able to reconcile the delivery with the batch reference of the pen.

Returns of items that are unused and unopened are accepted within the 14 days following delivery. Once a pen has been opened, or its tamper-evident seal has been broken, it can no longer be returned: that is the standard practice for sterile research consumables. If a parcel arrives damaged in transit, photograph the outer and inner packaging before opening it and contact us within the following 48 hours so that we can arrange, as far as inventory allows, a replacement from the same batch.

We ship to Spain in plain packaging; delivery generally takes 3–5 working days. Make provision for storage at 2–8 °C when you receive the goods.

Anyone who is still finalising the parameters of their protocol can consult the complete BPC-157 + TB-500 dosing protocol before ordering.

BPC-157 vs. TB-500: how they differ and why they are combined

BPC-157 is a pentadecapeptide derived from a gastric protein that acts locally on angiogenesis (VEGFR2), nitric oxide and collagen organisation; TB-500 is a fragment of thymosin beta-4 that regulates actin and, with it, systemic cell migration [3][1]. They are not interchangeable with one another, which is why they are investigated together rather than one being used in place of the other. The full comparison, with the evidence for each and what does not exist (no controlled trial of the combination), is in BPC-157 vs. TB-500 and in what is BPC-157 + TB-500.

Dosing guidance for research protocols

The figure on the dial is the dose of each peptide: 0.25 mg dialled delivers 0.25 mg of BPC-157 and 0.25 mg of TB-500. The reference schemes for this pen are a loading phase of 0.5 mg dialled once a day and a maintenance phase of 0.25 mg dialled once a day; with 16 mg of each peptide in the cartridge, the pen covers a complete cycle. The week-by-week calendar, the logic of loading and maintenance and the handling notes are in how to dose BPC-157 + TB-500.

Frequently Asked Questions

Is BPC-157 + TB-500 available in Spain for research purposes?

Yes, for the purposes of laboratory research. The product is not authorised as a medicine for either human or veterinary use, and buyers are responsible for complying with the research-governance framework of their own institution. Both peptides remain on the WADA prohibited list (TB-500 among the growth factors and growth-factor modulators of section S2; BPC-157 among the non-approved substances of section S0), which affects eligibility in sport independently of pharmaceutical legislation [6].

What level of purity does Body Pharm's BPC-157 + TB-500 have?

Every batch is released against an HPLC purity specification, with the exact percentage and the chromatogram stated on the batch-specific certificate of analysis that accompanies the order.

How, and for how long, should the pen be stored?

Keep the pen at between 2 and 8 °C and protected from light. While it is unopened, it keeps for 24 months. Once it has been punctured for the first time, use it within a period of 12 months. If you do not have a fridge available, the pen will tolerate up to 30 days at room temperature, with a maximum of 30 °C. Let it come up to room temperature before injecting and do not freeze it. The expiry date of the batch is shown on its CoA.

Can I get a certificate of analysis for my batch?

Yes. A CoA referenced to the batch is issued for every pen and is available on request either before or after purchase, with batch numbers that can be traced back to the filling and sealing record.

Does Body Pharm ship to any address in Spain?

Yes. All addresses in Spain are served with tracking for a flat shipping fee, and the tracking number is communicated to you at the time of dispatch.

Is it one pen or two?

It is a single pen. The two peptides are co-dissolved 50/50 in the same cartridge, 16 mg of each one, and they are administered together in a single injection from a single dial. The number you dial is the dose of each peptide. For a more detailed comparison of the molecules themselves, see BPC-157 vs. TB-500: how the two peptides compare.

Next steps

You now know how the BPC-157 + TB-500 blend works mechanistically, exactly what each number dialled on the dial delivers and what the status of the product is for use in research. Read the complete BPC-157 + TB-500 dosing protocol to confirm that the pen fits your study design, and then ask our support service for a certificate of analysis for the batch before going through to checkout, so that you can check the purity and identity data against the requirements of your institution.

Discover more research peptides from Body Pharm

If your research extends beyond BPC-157 + TB-500, there are some adjacent resources that may be of interest to you. The complete recovery peptides category brings the tissue-repair and regenerative compounds together in one place, while the peptide guides index collects protocol and comparison material. For anyone still at the evaluation stage, BPC-157 vs. TB-500: how the two peptides compare and GHK-Cu are, together with the dosing protocol, the most common next destinations.

Sources

1. Goldstein AL, et al. Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications. Expert Opin Biol Ther. 2012. pubmed.ncbi.nlm.nih.gov/22074294
2. Vasireddi N, et al. Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review. HSS J. 2025. pubmed.ncbi.nlm.nih.gov/40756949
3. Krivic A, et al. Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: promoted tendon-to-bone healing and opposed corticosteroid aggravation. J Orthop Res. 2006. pubmed.ncbi.nlm.nih.gov/16583442
4. Public product sheets from other research-peptide suppliers (consulted in 2026), used only to compare declared purity and the availability of the certificate of analysis. Commercial material, not peer-reviewed.
5. Directive 2001/83/EC, Article 1: definition of a medicinal product by presentation and by function; consolidated text on EUR-Lex. eur-lex.europa.eu — legal basis for the fact that a reagent labelled "for research only" remains subject to pharmaceutical regulation if it is presented for human use.
6. World Anti-Doping Agency (WADA), Prohibited List of substances and methods (current): section S0 (non-approved substances, which names BPC-157) and section S2 (peptide hormones, growth factors, related substances and mimetics, which names thymosin β4 and its derivatives, e.g. TB-500). wada-ama.org